Article
The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin.
Experimental cell research - 1 Aug 2004
Martens Nele, Wery Maxime, Wang Ping, Braet Filip, Gertler Arieh, Hooghe Robert, Vandenhaute Jean, Hooghe-Peters Elisabeth L
Abstract excerpt
To understand the function of the suppressor of cytokine signaling (SOCS)-7, we have looked for proteins interacting with SOCS-7 in a stringent yeast two-hybrid screen of a human leukocyte cDNA-library. We identified the cytoskeletal molecule vinexin as a partner interacting with SOCS-7. Tests with deletion mutants of SOCS-7 demonstrated that a central region of the molecule containing several proline-rich...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
