Article
Association of ADH4 genetic variants with alcohol dependence risk and related phenotypes: results from a larger multicenter association study.
Addiction biology - 1 Apr 2011
Preuss Ulrich W, Ridinger Monika, Rujescu Dan, Samochowiec Jerzy, Fehr Christoph, Wurst Friedrich M, Koller Gabriele, Bondy Brigitta, Wodarz Norbert, Debniak Tadeusz, Grzywacz Anna, Soyka Michael, Zill Peter
Abstract excerpt
Genetic variants of the alcohol-metabolizing enzyme ADH4, located on chromosome 4q22-4q23, have been related to alcohol dependence (AD) risk in previous research. The aim of this association study in a large multicenter sample of alcohol-dependent individuals and controls is to confirm ADH4 single nucleotide polymorphism (SNP) and haplotype association with AD and relevant related phenotypes. One thousand, six...
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