Article
Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus.
Journal of human genetics - 1 Jan 2002
Iida Aritoshi, Saito Susumu, Sekine Akihiro, Kondo Kimie, Mishima Chihiro, Kitamura Yuri, Harigae Satoko, Osawa Saori, Nakamura Yusuke
Abstract excerpt
The human alcohol dehydrogenase 4 (ADH4) gene encodes the class II ADH4 pi subunit, which contributes to the metabolization of a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Here we report the results of systematic screening for single-nucleotide polymorphisms (SNPs) in the ADH4 gene by means of direct sequencing combined with...
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