Article
Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication.
Human genetics - 1 Jun 2013
Park Byung Lae, Kim Jee Wook, Cheong Hyun Sub, Kim Lyoung Hyo, Lee Boung Chul, Seo Cheong Hoon, Kang Tae-Cheon, Nam Young-Woo, Kim Goon-Bo, Shin Hyoung Doo, Choi Ihn-Geun
Abstract excerpt
Alcohol dependence (AD) is a multifactorial and polygenic disorder involving complex gene-to-gene and gene-to-environment interactions. Several genome-wide association studies have reported numerous risk factors for AD, but replication results following these studies have been controversial. To identify new candidate genes, the present study used GWAS and replication studies in a Korean cohort with AD....
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