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Article

ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies.

Pharmacogenetics and genomics - 1 Nov 2005

Luo Xingguang, Kranzler Henry R, Zuo Lingjun, Yang Bao-zhu, Lappalainen Jaakko, Gelernter Joel

Abstract excerpt

We found strong associations between ADH4 gene variation and alcohol and drug dependence by the Hardy-Weinberg Disequilibrium (HWD) test and case-control association analysis in an initial study. The present study aimed to confirm these findings by controlling for population stratification and admixture effects to which the HWD test and case-control association methods may be vulnerable. In addition to 365...

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Source

Identifiers

PMID: 16220108
DOI: 10.1097/01.fpc.0000180141.77036.dc

Genes

ADH4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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