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Article

Association of genetic variants in alcohol dehydrogenase 4 with alcohol dependence in Brazilian patients.

The American journal of psychiatry - 1 May 2005

Guindalini Camila, Scivoletto Sandra, Ferreira Ricardo G M, Breen Gerome, Zilberman Monica, Peluso Marco Aurélio, Zatz Mayana

Abstract excerpt

OBJECTIVE: The authors evaluated the association of three functional promoter polymorphisms of the ADH4 gene with alcohol dependence. METHOD: DNA from 92 alcohol-dependent patients and 92 healthy comparison subjects was genotyped for all three polymorphisms. RESULTS: Variants at the -75 base-pair (bp) (C allele) and -159 bp (A allele) positions were associated with alcohol dependence. Individuals with haplotypes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15863808
DOI: 10.1176/appi.ajp.162.5.1005

Genes

ADH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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