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Article

Study on the relationship between cyclodextrin glycosyltransferase's thermostability and salt bridge by molecular dynamics simulation.

Protein and peptide letters - 1 Nov 2010

Fu Yi, Ding Yanrui, Chen Zhiguo, Sun Jun, Fang Wei, Xu Wenbo

Abstract excerpt

Cyclodextrin glycosyltransferase (EC 2.4.1.19, CGTase) is an important industrial enzyme in the production of cyclodextrins. Thermal stability is of great importance for this enzyme. Rational design of thermostable variants of mesophilic proteins is well motivated. In this work, molecular dynamics simulations have been performed to study thermal stabilization of CGTase protein via electrostatic interactions of...

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PMID: 20594159
DOI: 10.2174/0929866511009011403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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