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Article

Computational approach for designing thermostable Candida antarctica lipase B by molecular dynamics simulation.

Journal of biotechnology - 20 Dec 2014

Park Hyun June, Park Kyungmoon, Kim Yong Hwan, Yoo Young Je

Abstract excerpt

Candida antarctica lipase B (CalB) is one of the most useful enzyme for various reactions and bioconversions. Enhancing thermostability of CalB is required for industrial applications. In this study, we propose a computational design strategy to improve the thermostability of CalB. Molecular dynamics simulations at various temperatures were used to investigate the common fluctuation sites in CalB, which are...

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Identifiers

PMID: 25270022
DOI: 10.1016/j.jbiotec.2014.09.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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