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Article

FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population.

Journal of lipid research - 1 Sept 2010

Mathias Rasika A, Vergara Candelaria, Gao Li, Rafaels Nicholas, Hand Tracey, Campbell Monica, Bickel Carol, Ivester Priscilla, Sergeant Susan, Barnes Kathleen C, Chilton Floyd H

Abstract excerpt

Long-chain polyunsaturated fatty acids (PUFA) orchestrate immunity and inflammation through their capacity to be converted to potent inflammatory mediators. We assessed associations of FADS gene cluster polymorphisms and fasting serum PUFA concentrations in a fully ascertained, geographically isolated founder population of European descent. Concentrations of 22 PUFAs were determined by gas chromatography, of...

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Source

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Identifiers

PMID: 20562440
DOI: 10.1194/jlr.M008359
PMCID: PMC2918459

Genes

FADS1
FADS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population.PMID 20562440Read ↗

FADS1 and FADS2 Polymorphisms Modulate Fatty Acid Metabolism and Dietary Impact on HealthSemantic proximity Read ↗

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The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans.Semantic proximity Read ↗

Identification of a functional FADS1 3'UTR variant associated with erythrocyte n-6 polyunsaturated fatty acids levels.Semantic proximity Read ↗

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Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios.Semantic proximity Read ↗

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