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Article

FADS2 polymorphisms are associated with plasma arachidonic acid and estimated desaturase-5 activity in a cross-sectional study.

Nutrition research (New York, N.Y.) - 1 Nov 2020

Zec Manja M, Stojković Ljiljana, Zeković Milica, Pokimica Biljana, Zivkovic Maja, Stankovic Aleksandra, Glibetic Maria

Abstract excerpt

Polymorphisms in FADS genes are associated with plasma long-chain polyunsaturated fatty acids (LC-PUFA) and modulate omega-6/omega-3 balance. We hypothesized that the FADS2 gene variants will be associated with lower product-to-precursor ratio in the fatty acid metabolic pathways. Thus, we explored FADS2 rs174593, rs174616, and rs174576 effects on plasma phospholipid fatty acid profile, markers of desaturase...

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Share to Arachidonic Acid
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PMID: 33011673
DOI: 10.1016/j.nutres.2020.08.010

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