Article
The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans.
BMC genetics - 20 May 2011
Mathias Rasika A, Sergeant Susan, Ruczinski Ingo, Torgerson Dara G, Hugenschmidt Christina E, Kubala Meghan, Vaidya Dhananjay, Suktitipat Bhoom, Ziegler Julie T, Ivester Priscilla, Case Douglas, Yanek Lisa R, Freedman Barry I, Rudock Megan E, Barnes Kathleen C, Langefeld Carl D, Becker Lewis C, Bowden Donald W, Becker Diane M, Chilton Floyd H
Abstract excerpt
BACKGROUND: Arachidonic acid (AA) is a long-chain omega-6 polyunsaturated fatty acid (PUFA) synthesized from the precursor dihomo-gamma-linolenic acid (DGLA) that plays a vital role in immunity and inflammation. Variants in the Fatty Acid Desaturase (FADS) family of genes on chromosome 11q have been shown to play a role in PUFA metabolism in populations of European and Asian ancestry; no work has been done in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.