Article
Variation in the FADS1/2 gene cluster alters plasma n-6 PUFA and is weakly associated with hsCRP levels in healthy young adults.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Sept 2013
Roke Kaitlin, Ralston Jessica C, Abdelmagid Salma, Nielsen Daiva E, Badawi Alaa, El-Sohemy Ahmed, Ma David W L, Mutch David M
Abstract excerpt
INTRODUCTION: Past research has reported that single nucleotide polymorphisms (SNPs) in fatty acid desaturase 1 and 2 (FADS1/2) can influence plasma fatty acid (FA) profiles. Changes in FA profiles are known to influence inflammatory processes; therefore both FA and SNPs in FADS1/2 may affect inflammation. The goals of this study were to (i) examine the relationships between individual n-6 FA and estimates of FA...
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