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Article

T cells recognizing an HLA-DQ alpha beta heterodimer encoded in cis by the DR4DQw4 haplotype and in trans by DR4DQw8/DRw8DQw4 heterozygous cells.

Human immunology - 1 Mar 1991

Gjertsen H A, Lundin K E, Rønningen K S, Gaudernack G, Thorsby E

Abstract excerpt

We generated alloreactive DQ-specific CD4+ T-lymphocyte clones. One of these (TLC HH58) was only restimulated with cells having the DR4DQw4 haplotype or cells being DR4DQw8/DRw8DQw4 heterozygous. The former cells carry the DQA1*0301 and DQB1*0401 alleles in cis position while the latter cells carry DQA1*0301 and DQB1*0402 alleles (DQB1*0402 is identical to DQB1*0401 except for codon 23) in trans position. Thus,...

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Source

Identifiers

PMID: 2055788
DOI: 10.1016/0198-8859(91)90039-c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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