Article
Positive correlation between oligonucleotide typing and T-cell recognition of HLA-DP molecules.
Immunogenetics - 1 Jan 1991
de Koster H S, Kenter M J, D'Amaro J, Luiten R M, Schroeijers W E, Giphart M J, Termijtelen A
Abstract excerpt
The identification of 19 different HLA-DPB1 sequences implicates the existence of more DP specificities than can be typed for with cellular methods. How many of the DP beta sequences can be specifically recognized by T cells, and which of the polymorphic regions can contribute to the specificity of allorecognition, is not known. In order to investigate the distribution and the immunological relevance of recently...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Blotting, Southern
- Epitopes
- Female
- Gene Frequency
- HLA-DP Antigens
- Humans
- Immunophenotyping
- Male
- Molecular Sequence Data
