Article
T cell recognition of self-human histocompatibility leukocyte antigens (HLA)-DR peptides in context of syngeneic HLA-DR molecules.
The Journal of experimental medicine - 1 Jun 1992
Liu Z, Sun Y K, Xi Y P, Harris P, Suciu-Foca N
Abstract excerpt
It has been suggested that self major histocompatibility complex (MHC) peptides bound to self MHC molecules may be involved in the intrathymic induction of self tolerance. We studied the antigenicity of synthetic peptides derived from the first domain of DR beta 1*0101 chain in a DR beta 1*0101 r...
Topics
- Antibodies, Monoclonal
- Cells, Cultured
- Clone Cells
- Epitopes
- Genotype
- HLA-DR Antigens
- Histocompatibility Antigens Class I
- Histocompatibility Testing
- Humans
- Immune Tolerance
- Lymphocyte Activation
- Male
- Peptides
- T-Lymphocytes