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Article

T lymphocyte recognition of a celiac disease-associated cis- or trans-encoded HLA-DQ alpha/beta-heterodimer.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 1990

Lundin K E, Sollid L M, Qvigstad E, Markussen G, Gjertsen H A, Ek J, Thorsby E

Abstract excerpt

The HLA-associated susceptibility to develop celiac disease may to a large extent be attributed to the combination of particular DQA1 and DQB1 genes, i.e., the DQA1*0501 and DBQB1*0201 alleles, located either in cis position (on the DR3DQw2 haplotype) or in trans position (DR5DQw7/DR7DQw2 heterozygous individuals). We report three alloreactive T lymphocyte clones that recognize an HLA-DQ alpha/beta heterodimer...

Topics

Alleles
Antibodies, Monoclonal
Base Sequence
CD4-Positive T-Lymphocytes
Celiac Disease
Cell Separation
Cloning, Molecular
HLA-DQ Antigens
Humans
Lymphocyte Activation
Macromolecular Substances

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Oligonucleotide Probes

Source

Identifiers

PMID: 1972714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1972714-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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T lymphocyte recognition of a celiac disease-associated cis- or trans-encoded HLA-DQ alpha/beta-heterodimer.PMID 1972714Read ↗

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