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Article

Alloreactive T-cell clones identify multiple HLA-DQw3 variants.

Human immunology - 1 Jan 1991

Mickelson E M, Masewicz S A, Nepom G T, Martin P J, Hansen J A

Abstract excerpt

HLA-DQw3 is a broadly defined alloantigen that has been subdivided by serological, biochemical, and molecular methods into three distinct specificities: DQw7, DQw8, and DQw9. In order to characterize functionally relevant structural polymorphisms within this family of alloantigens, we generated a series of DQw3-reactive T-cell clones that together recognize six different variants of DQw3. T-cell clones IG11 and...

Topics

Alleles
Amino Acid Sequence
Clone Cells
Epitopes
Genetic Variation
HLA-DQ Antigens
Humans
Molecular Sequence Data
T-Lymphocytes

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1705927
DOI: 10.1016/0198-8859(91)90068-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1705927-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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