Article
Alloreactive T-cell clones identify multiple HLA-DQw3 variants.
Human immunology - 1 Jan 1991
Mickelson E M, Masewicz S A, Nepom G T, Martin P J, Hansen J A
Abstract excerpt
HLA-DQw3 is a broadly defined alloantigen that has been subdivided by serological, biochemical, and molecular methods into three distinct specificities: DQw7, DQw8, and DQw9. In order to characterize functionally relevant structural polymorphisms within this family of alloantigens, we generated a series of DQw3-reactive T-cell clones that together recognize six different variants of DQw3. T-cell clones IG11 and...
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