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Article

Structural characterization of the Get4/Get5 complex and its interaction with Get3.

Proceedings of the National Academy of Sciences of the United States of America - 6 Jul 2010

Chartron Justin W, Suloway Christian J M, Zaslaver Ma'ayan, Clemons William M

Abstract excerpt

The recently elucidated Get proteins are responsible for the targeted delivery of the majority of tail-anchored (TA) proteins to the endoplasmic reticulum. Get4 and Get5 have been identified in the early steps of the pathway mediating TA substrate delivery to the cytoplasmic targeting factor Get3. Here we report a crystal structure of Get4 and an N-terminal fragment of Get5 from Saccharomyces cerevisae. We show...

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Share to Adenosine Triphosphatases
Share to Crystallography, X-Ray

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Guanine Nucleotide Exchange Factors

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Identifiers

PMID: 20554915
DOI: 10.1073/pnas.1006036107
PMCID: PMC2901463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural characterization of the Get4/Get5 complex and its interaction with Get3.PMID 20554915Read ↗

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