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Article

The GET System Inserts the Tail-Anchored Protein, SYP72, into Endoplasmic Reticulum Membranes.

Plant physiology - 1 Feb 2017

Srivastava Renu, Zalisko Benjamin E, Keenan Robert J, Howell Stephen H

Abstract excerpt

The Arabidopsis (Arabidopsis thaliana) genome encodes homologs of the Guided Entry of Tail (GET)-anchored protein system for the posttranslational insertion of tail-anchored (TA) proteins into endoplasmic reticulum (ER) membranes. In yeast, TA proteins are loaded onto the cytosolic targeting fact...

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Identifiers

PMID: 27923985
DOI: 10.1104/pp.16.00928
PMCID: PMC5291014

Genes

GET1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-27923985-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The GET System Inserts the Tail-Anchored Protein, SYP72, into Endoplasmic Reticulum Membranes.PMID 27923985Read ↗

Endoplasmic reticulum membrane receptors of the GET pathway are conserved throughout eukaryotes.Semantic proximity Read ↗

Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast.Semantic proximity Read ↗

Structural characterization of the Get4/Get5 complex and its interaction with Get3.Semantic proximity Read ↗

A chaperone cascade sorts proteins for posttranslational membrane insertion into the endoplasmic reticulum.Semantic proximity Read ↗

The Get1/2 transmembrane complex is an endoplasmic-reticulum membrane protein insertase.Semantic proximity Read ↗

A phosphoinositide-mediated switch of GET pathway receptor dimerization in Arabidopsis.Semantic proximity Read ↗

Subunit cooperation in the Get1/2 receptor promotes tail-anchored membrane protein insertion.Semantic proximity Read ↗

Characterisation of guided entry of tail-anchored proteins in <i>Magnaporthe oryzae</i>Semantic proximity Read ↗

A conserved Guided Entry of Tail-anchored pathway is involved in the trafficking of tail-anchored membrane proteins in <i>Plasmodium falciparum</i>Semantic proximity Read ↗

Model for eukaryotic tail-anchored protein binding based on the structure of Get3.Semantic proximity Read ↗

Cooperative and independent activities of Sgt2 and Get5 in the targeting of tail-anchored proteins.Semantic proximity Read ↗

The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae.Semantic proximity Read ↗

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