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Article

Model for eukaryotic tail-anchored protein binding based on the structure of Get3.

Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 2009

Suloway Christian J M, Chartron Justin W, Zaslaver Ma'ayan, Clemons William M

Abstract excerpt

The Get3 ATPase directs the delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (ER). TA-proteins are characterized by having a single transmembrane helix (TM) at their extreme C terminus and include many essential proteins, such as SNAREs, apoptosis factors, and protein translocation components. These proteins cannot follow the SRP-dependent co-translational pathway that typifies most integral...

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Identifiers

PMID: 19706470
DOI: 10.1073/pnas.0907522106
PMCID: PMC2736419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Model for eukaryotic tail-anchored protein binding based on the structure of Get3.PMID 19706470Read ↗

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