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Article

A chaperone cascade sorts proteins for posttranslational membrane insertion into the endoplasmic reticulum.

Molecular cell - 8 Oct 2010

Wang Fei, Brown Emily C, Mak Gary, Zhuang Jimmy, Denic Vladimir

Abstract excerpt

Tail-anchored (TA) proteins are posttranslationally inserted into either the endoplasmic reticulum (ER) or the mitochondrial outer membrane. The C-terminal transmembrane domains (TMDs) of TA proteins enable their many essential cellular functions by specifying the membrane target, but how cells p...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20850366
DOI: 10.1016/j.molcel.2010.08.038
PMCID: PMC3652556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20850366-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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