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Article

Antibiotic resistance markers for genetic manipulations of Leptospira spp.

Applied and environmental microbiology - 1 Jul 2010

Poggi Dante, Oliveira de Giuseppe Priscila, Picardeau Mathieu

Abstract excerpt

We measured the frequency of appearance of spontaneous mutants resistant to gentamicin, kanamycin, streptomycin, and spectinomycin in saprophytic and pathogenic Leptospira strains. The mutations responsible for the spontaneous resistance to streptomycin and spectinomycin were identified in the rpsL and rrs genes, respectively. We also generated a gentamicin resistance cassette that allows the use of a third...

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Identifiers

PMID: 20511419
DOI: 10.1128/AEM.00775-10
PMCID: PMC2901752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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