Article
Transposon Sequencing in Leptospira interrogans.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Lourdault Kristel, Matsunaga James
Abstract excerpt
Our limited understanding of the relationship of genotype to phenotype in the spirochete Leptospira interrogans stems from the inefficiency of the genetic tools available to manipulate the pathogen. The recent development of random transposon mutagenesis in L. interrogans has allowed the creation of large libraries of mutants, permitting the identification of several genes involved in certain functions such as...
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