Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acquisition of certain streptomycin-resistant (str) mutations enhances antibiotic production in bacteria.

Antimicrobial agents and chemotherapy - 1 Aug 1998

Hosoya Y, Okamoto S, Muramatsu H, Ochi K

Abstract excerpt

Physiological differentiation (including antibiotic production) in microorganisms usually starts when cells encounter adverse environmental conditions and is frequently accompanied by an increase in the accumulation of intracellular ppGpp. We have found that the acquisition of certain streptomycin-resistant (str) mutations enables cells to overproduce antibiotics, demonstrating an increase in productivity 5- to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Anti-Bacterial Agents
Share to Bacillus subtilis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bacteria

Share to Drug Resistance, Microbial

Share to Escherichia coli Proteins

Share to Mutation

Share to Pseudomonas

Source

Open in PubMed Open full text

Identifiers

PMID: 9687404
DOI: 10.1128/AAC.42.8.2041
PMCID: PMC105730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acquisition of certain streptomycin-resistant (str) mutations enhances antibiotic production in bacteria.PMID 9687404Read ↗

Activation of secondary metabolite-biosynthetic gene clusters by generating rsmG mutations in Streptomyces griseus.Semantic proximity Read ↗

Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Development of antibiotic-overproducing strains by site-directed mutagenesis of the rpsL gene in Streptomyces lividans.Semantic proximity Read ↗

Mechanisms of streptomycin resistance: selection of mutations in the 16S rRNA gene conferring resistance.Semantic proximity Read ↗

Innovative approach for improvement of an antibiotic-overproducing industrial strain of Streptomyces albus.Semantic proximity Read ↗

Introduction of Spontaneous Mutations Using Streptomycin as a Method for Lactic Acid Bacteria Breeding.Semantic proximity Read ↗

Novel approach for improving the productivity of antibiotic-producing strains by inducing combined resistant mutations.Semantic proximity Read ↗

Genetically engineered rpsL merodiploidy impacts secondary metabolism and antibiotic resistance in Streptomyces.Semantic proximity Read ↗

The fitness cost of streptomycin resistance depends on rpsL mutation, carbon source and RpoS (sigmaS).Semantic proximity Read ↗

An ABC transporter involved in the control of streptomycin production in Streptomyces griseus.Semantic proximity Read ↗

Growth rate effects of mutations conferring streptomycin-dependence and of ancillary mutations in the rpsL gene of Escherichia coli: implications for the clustering (hypermutation) hypothesis for spontaneous mutation.Semantic proximity Read ↗

Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.