Article
DDOST, PRKCSH and LGALS3, which encode AGE-receptors 1, 2 and 3, respectively, are not associated with diabetic nephropathy in type 1 diabetes.
Diabetologia - 1 Sept 2010
Hoverfelt A, Sallinen R, Söderlund J M, Forsblom C, Pettersson-Fernholm K, Parkkonen M, Groop P-H, Wessman M
Abstract excerpt
AIMS/HYPOTHESIS: The AGE receptors 1, 2 and 3, which are encoded by DDOST, PRKCSH and LGALS3, respectively, may be involved in the pathogenesis of diabetic complications. We sought to find out whether these genes are associated with diabetic nephropathy, cardiovascular disease and type 1 diabetes or related quantitative traits. METHODS: Using the Tagger program, we selected 28 single nucleotide polymorphisms...
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