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Article

Association analysis of podocyte slit diaphragm genes as candidates for diabetic nephropathy.

Diabetologia - 1 Jan 2008

Ihalmo P, Wessman M, Kaunisto M A, Kilpikari R, Parkkonen M, Forsblom C, Holthöfer H, Groop P-H

Abstract excerpt

AIMS/HYPOTHESIS: The slit diaphragm is an adhesion and signalling protein complex linking the interdigitating podocyte foot processes in the kidney glomerulus, and mutations in slit diaphragm-associated genes result in severe proteinuria. Here we report a genetic association analysis of four slit diaphragm genes, LRRC7, KIRREL, NPHS2 and ACTN4, in a Finnish diabetic nephropathy cohort. MATERIALS AND METHODS: A...

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Source

Identifiers

PMID: 17968527
DOI: 10.1007/s00125-007-0854-2

Genes

ACTN4
NPHS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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