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Article

Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy.

Diabetologia - 1 Nov 2008

Savage D A, Patterson C C, Deloukas P, Whittaker P, McKnight A J, Morrison J, Boulton A J, Demaine A G, Marshall S M, Millward B A, Thomas S M, Viberti G C, Walker J D, Sadlier D, Maxwell A P, Bain S C

Abstract excerpt

AIMS/HYPOTHESIS: Diabetic nephropathy, characterised by persistent proteinuria, hypertension and progressive kidney failure, affects a subset of susceptible individuals with diabetes. It is also a leading cause of end-stage renal disease (ESRD). Non-synonymous (ns) single nucleotide polymorphisms (SNPs) have been reported to contribute to genetic susceptibility in both monogenic disorders and common complex...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18773191
DOI: 10.1007/s00125-008-1142-5
PMCID: PMC2687720

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Source receipt: pubmed, retrieved 7 Sept 2026.

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