Article
Association of the SLC22A1, SLC22A2, and SLC22A3 genes encoding organic cation transporters with diabetic nephropathy and hypertension.
Annals of medicine - 6 May 2010
Sallinen Riitta, Kaunisto Mari A, Forsblom Carol, Thomas Merlin, Fagerudd Johan, Pettersson-Fernholm Kim, Groop Per-Henrik, Wessman Maija
Abstract excerpt
BACKGROUND: Diabetic nephropathy (DN) is a severe long-term complication of diabetes characterized by continuous albuminuria, a relentless decline in renal function, and an increased arterial blood pressure. AIMS: Our aim was to find out if single nucleotide polymorphisms (SNPs) within the SLC22A1, SLC22A2, and SLC22A3 genes encoding organic cation transporters (OCTs) associate with DN or hypertension. SUBJECTS...
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