Article
Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe).
Investigative ophthalmology & visual science - 29 Sept 2011
Sobrin Lucia, Green Todd, Sim Xueling, Jensen Richard A, Tai E Shyong, Tay Wan Ting, Wang Jie Jin, Mitchell Paul, Sandholm Niina, Liu Yiyuan, Hietala Kustaa, Iyengar Sudha K, Brooks Matthew, Buraczynska Monika, Van Zuydam Natalie, Smith Albert V, Gudnason Vilmundur, Doney Alex S F, Morris Andrew D, Leese Graham P, Palmer Colin N A, Swaroop Anand, Taylor Herman A, Wilson James G, Penman Alan, Chen Ching J, Groop Per-Henrik, Saw Seang-Mei, Aung Tin, Klein Barbara E, Rotter Jerome I, Siscovick David S, Cotch Mary Frances, Klein Ronald, Daly Mark J, Wong Tien Y
Abstract excerpt
PURPOSE: To investigate whether variants in cardiovascular candidate genes, some of which have been previously associated with type 2 diabetes (T2D), diabetic retinopathy (DR), and diabetic nephropathy (DN), are associated with DR in the Candidate gene Association Resource (CARe). METHODS: Persons with T2D who were enrolled in the study (n = 2691) had fundus photography and genotyping of single nucleotide...
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