Article
Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.
Diabetes - 1 Jun 2009
Pezzolesi Marcus G, Poznik G David, Mychaleckyj Josyf C, Paterson Andrew D, Barati Michelle T, Klein Jon B, Ng Daniel P K, Placha Grzegorz, Canani Luis H, Bochenski Jacek, Waggott Daryl, Merchant Michael L, Krolewski Bozena, Mirea Lucia, Wanic Krzysztof, Katavetin Pisut, Kure Masahiko, Wolkow Pawel, Dunn Jonathon S, Smiles Adam, Walker William H, Boright Andrew P, Bull Shelley B, Doria Alessandro, Rogus John J, Rich Stephen S, Warram James H, Krolewski Andrzej S
Abstract excerpt
OBJECTIVE: Despite extensive evidence for genetic susceptibility to diabetic nephropathy, the identification of susceptibility genes and their variants has had limited success. To search for genes that contribute to diabetic nephropathy, a genome-wide association scan was implemented on the Genetics of Kidneys in Diabetes collection. RESEARCH DESIGN AND METHODS: We genotyped approximately 360,000 single...
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