Article
Novel genetic susceptibility loci for diabetic end-stage renal disease identified through robust naive Bayes classification.
Diabetologia - 1 Aug 2014
Sambo Francesco, Malovini Alberto, Sandholm Niina, Stavarachi Monica, Forsblom Carol, Mäkinen Ville-Petteri, Harjutsalo Valma, Lithovius Raija, Gordin Daniel, Parkkonen Maija, Saraheimo Markku, Thorn Lena M, Tolonen Nina, Wadén Johan, He Bing, Osterholm Anne-May, Tuomilehto Jaako, Lajer Maria, Salem Rany M, McKnight Amy Jayne, Tarnow Lise, Panduru Nicolae M, Barbarini Nicola, Di Camillo Barbara, Toffolo Gianna M, Tryggvason Karl, Bellazzi Riccardo, Cobelli Claudio, Groop Per-Henrik
Abstract excerpt
AIMS/HYPOTHESIS: Diabetic nephropathy is a major diabetic complication, and diabetes is the leading cause of end-stage renal disease (ESRD). Family studies suggest a hereditary component for diabetic nephropathy. However, only a few genes have been associated with diabetic nephropathy or ESRD in diabetic patients. Our aim was to detect novel genetic variants associated with diabetic nephropathy and ESRD. METHODS:...
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