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Article

Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus.

European journal of human genetics : EJHG - 1 Sept 2010

Morris David L, Roberts Amy L, Witherden Abigail S, Tarzi Ruth, Barros Paula, Whittaker John C, Cook Terence H, Aitman Timothy J, Vyse Timothy J

Abstract excerpt

The Fcgamma-receptor locus on chromosome 1q23 shows copy-number variation (CNV), and it has previously been shown that individuals with reduced numbers of copies of the Fcgamma-receptor-IIIB gene (FCGR3B) have an increased risk of developing systemic lupus erythematosus (SLE). It is not understood whether the association arises from FCGR3B (CD16b) itself, is observed because of linkage disequilibrium with actual...

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Identifiers

PMID: 20442749
DOI: 10.1038/ejhg.2010.56
PMCID: PMC2987408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus.PMID 20442749Read ↗

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