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Article

A comparison of assays for accurate copy number measurement of the low-affinity Fc gamma receptor genes FCGR3A and FCGR3B.

PloS one - 1 Jan 2015

Haridan Umi Shakina, Mokhtar Umairah, Machado Lee R, Abdul Aziz Abu Thalhah, Shueb Rafidah Hanim, Zaid Masliza, Sim Benedict, Mustafa Mahiran, Nik Yusof Nik Khairudin, Lee Christopher K C, Abu Bakar Suhaili, AbuBakar Sazaly, Hollox Edward J, Boon Peng Hoh

Abstract excerpt

The FCGR3 locus encoding the low affinity activating receptor FcγRIII, plays a vital role in immunity triggered by cellular effector and regulatory functions. Copy number of the genes FCGR3A and FCGR3B has previously been reported to affect susceptibility to several autoimmune diseases and chronic inflammatory conditions. However, such genetic association studies often yield inconsistent results; hence require...

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Identifiers

PMID: 25594501
DOI: 10.1371/journal.pone.0116791
PMCID: PMC4297192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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