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Article

Association of variation in Fcgamma receptor 3B gene copy number with rheumatoid arthritis in Caucasian samples.

Annals of the rheumatic diseases - 1 Sept 2010

McKinney Cushla, Fanciulli Manuela, Merriman Marilyn E, Phipps-Green Amanda, Alizadeh Behrooz Z, Koeleman Bobby P C, Dalbeth Nicola, Gow Peter J, Harrison Andrew A, Highton John, Jones Peter B, Stamp Lisa K, Steer Sophia, Barrera Pilar, Coenen Marieke J H, Franke Barbara, van Riel Piet L C M, Vyse Tim J, Aitman Tim J, Radstake Timothy R D J, Merriman Tony R

Abstract excerpt

OBJECTIVE: There is increasing evidence that variation in gene copy number (CN) influences clinical phenotype. The low-affinity Fcgamma receptor 3B (FCGR3B) located in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment to sites of inflammation and activation of polymorphon...

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Identifiers

PMID: 20472591
DOI: 10.1136/ard.2009.123588
PMCID: PMC3670580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20472591-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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