Article
Genetic variation of the Fc gamma receptor 3B gene and association with rheumatoid arthritis.
PloS one - 5 Oct 2010
Marques Rute B, Thabet Mohamed M, White Stefan J, Houwing-Duistermaat Jeanine J, Bakker Aleida M, Hendriks Gert-Jan, Zhernakova Alexandra, Huizinga Tom W, van der Helm-van Mil Annette H, Toes Rene E
Abstract excerpt
BACKGROUND: Fc gamma receptors (FcγRs) play a crucial role in immunity by linking IgG antibody-mediated responses with cellular effector and regulatory functions. Genetic variants in these receptors have been previously identified as risk factors for several chronic inflammatory conditions. The p...
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