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Article

An integrated approach for measuring copy number variation at the FCGR3 (CD16) locus.

Human mutation - 1 Mar 2009

Hollox Edward J, Detering Jan-Christoph, Dehnugara Tushna

Abstract excerpt

Copy number variation (CNV) is an important source of genomic diversity in humans, and influences disease susceptibility. The immunoglobulin-receptor genes FCGR3A and FCGR3B on chromosome 1q23.3 show CNV, and CNV of the FCGR3B gene is associated with glomerulonephritis in systemic lupus erythematosus and organ-specific autoimmunity. Large-scale case-control association studies of CNV require technologies that are...

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Identifiers

PMID: 19143032
DOI: 10.1002/humu.20911
PMCID: PMC3600569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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An integrated approach for measuring copy number variation at the FCGR3 (CD16) locus.PMID 19143032Read ↗

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