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Article

Targeted Vezf1-null mutation impairs vascular structure formation during embryonic stem cell differentiation.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2010

Zou Zhongmin, Ocaya Pauline A, Sun Huiqin, Kuhnert Frank, Stuhlmann Heidi

Abstract excerpt

OBJECTIVE: Vezf1 encodes an early zinc finger transcription factor that is essential for normal vascular development and functions in a dose-dependent manner. Here, we investigated the role of Vezf1 during processes of endothelial cell differentiation and maturation by studying mutant Vezf1 embryonic stem (ES) cells using the in vitro embryoid body differentiation model and the in vivo teratocarcinoma model....

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Source

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Identifiers

PMID: 20431070
DOI: 10.1161/ATVBAHA.109.200428
PMCID: PMC2903440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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