Article

Investigating the role of the human transcription factor VEZF1 in erythroid and vascular endothelial differentiation

2017-01-01

Abstract excerpt

VEZF1 is a ubiquitously expressed transcription factor with epigenetic roles at gene regulatory elements, including protection from DNA methylation. Genetic ablation of Vezf1 in murine embryos is lethal due to haemorrhages localised in head and neck mainly. Interestingly, Vezf1 seems to be important for the generation of erythroid cells. The role of human VEZF1 in erythroid gene regulation was the primary focus of...

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Literature Corpus work: 5081b5a1-286d-516b-9d67-bf494e41f3e9
DOI: 10.5525/gla.thesis.8337

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