Article

Fate and state transitions during human blood vessel organoid development

2022-03-23

Abstract excerpt

Blood vessel organoids (BVOs) derived from human pluripotent stem cells have emerged as a novel system to understand human vascular development, model disorders, and develop regenerative therapies. However, it is unclear which molecular states constitute BVOs and how cells differentiate and self-organize within BVOs in vitro and after transplantation. Here we reconstruct BVO development over a time course using s...

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Literature Corpus work: f3664d5e-6698-51a7-ab48-124a91e938ac
DOI: 10.1101/2022.03.23.485329

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