Article
Endothelial differentiation: molecular mechanisms of specification and heterogeneity.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2011
Atkins G Brandon, Jain Mukesh K, Hamik Anne
Abstract excerpt
A complex and diverse vascular system is requisite for the survival of higher organisms. The process of vascular development is highly regulated, involving the de novo formation of vessels (vasculogenesis), followed by expansion and remodeling of the primitive vasculature (angiogenesis), culminating in differentiation of endothelial phenotypes, as found in the mature vascular system. Over the last decade,...
Topics
- Animals
- Arteries
- Body Patterning
- Cell Differentiation
- Cell Lineage
- Cell Proliferation
- Endothelial Cells
- Gene Expression Regulation, Developmental
- Humans
- Lymphatic Vessels
- Neovascularization, Physiologic