Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA DPA1, DPB1 alleles and haplotypes contribute to the risk associated with type 1 diabetes: analysis of the type 1 diabetes genetics consortium families.

Diabetes - 1 Aug 2010

Varney Michael D, Valdes Ana Maria, Carlson Joyce A, Noble Janelle A, Tait Brian D, Bonella Persia, Lavant Eva, Fear Anna Lisa, Louey Anthony, Moonsamy Priscilla, Mychaleckyj Josyf C, Erlich Henry

Abstract excerpt

OBJECTIVE: To determine the relative risk associated with DPA1 and DPB1 alleles and haplotypes in type 1 diabetes. RESEARCH DESIGN AND METHODS: The frequency of DPA1 and DPB1 alleles and haplotypes in type 1 diabetic patients was compared to the family based control frequency in 1,771 families directly and conditional on HLA (B)-DRB1-DQA1-DQB1 linkage disequilibrium. A relative predispositional analysis (RPA) was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to Family

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to HLA Antigens

Share to HLA-DP alpha-Chains

Share to HLA-DP Antigens

Share to HLA-DP beta-Chains

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 20424227
DOI: 10.2337/db09-0680
PMCID: PMC2911060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA DPA1, DPB1 alleles and haplotypes contribute to the risk associated with type 1 diabetes: analysis of the type 1 diabetes genetics consortium families.PMID 20424227Read ↗

The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes.Semantic proximity Read ↗

HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families.Semantic proximity Read ↗

The HLA-DPB1--associated component of the IDDM1 and its relationship to the major loci HLA-DQB1, -DQA1, and -DRB1.Semantic proximity Read ↗

DPB1 alleles are associated with type 1 diabetes susceptibility in multiple ethnic groups.Semantic proximity Read ↗

Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis.Semantic proximity Read ↗

HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium.Semantic proximity Read ↗

HLA associations in type 1 diabetes: DPB1 alleles may act as markers of other HLA-complex susceptibility genes.Semantic proximity Read ↗

Association of HLA-DPB1 alleles with type I diabetes mellitus in Slovak population.Semantic proximity Read ↗

Genetics of the HLA region in the prediction of type 1 diabetes.Semantic proximity Read ↗

HLA DPB1*0201 gene confers disease susceptibility in japanese with childhood onset type I diabetes, independent of HLA-DR and DQ genotypes.Semantic proximity Read ↗

Analysis of the role of DPB1-encoded amino acids in the genetic predisposition to type I diabetes mellitus.Semantic proximity Read ↗

Type 1 diabetes risk for human leukocyte antigen (HLA)-DR3 haplotypes depends on genotypic context: association of DPB1 and HLA class I loci among DR3- and DR4-matched Italian patients and controls.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.