Article
The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes.
Diabetes - 1 Jan 2000
Noble J A, Valdes A M, Thomson G, Erlich H A
Abstract excerpt
HLA-DPB1 genotypes were determined for samples from 269 multiplex Caucasian families from the Human Biological Data Interchange. DRB1 and DQB1 loci were also characterized, allowing assignment of DPB1 alleles to haplotypes and calculation of linkage disequilibrium values. Frequencies for several DPB1 alleles differed significantly between patients and affected family-based control subjects. Some differences were...
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