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Article

HLA DPB1*0201 gene confers disease susceptibility in japanese with childhood onset type I diabetes, independent of HLA-DR and DQ genotypes.

Diabetes research and clinical practice - 1 Jan 2000

Nishimaki K, Kawamura T, Inada H, Yagawa K, Nose Y, Nabeya N, Isshiki G, Tatsumi N, Niihira S

Abstract excerpt

HLA is an important etiologic genetic factor in Type I diabetes and specific HLA-class II genes are closely related to the onset of the disease. Many differences in the patterns of susceptible and resistant DRB1, DQA1, and DQB1 genes have been observed among various ethnic groups. We have previously shown that DRB1*0405, DRB1*0901 and DQA1*0301-DQB1*0302 were the major susceptible alleles or haplotype to Type I...

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PMID: 10660221
DOI: 10.1016/s0168-8227(99)00103-5

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