Article
DPB1 alleles are associated with type 1 diabetes susceptibility in multiple ethnic groups.
Diabetes - 1 Aug 2004
Cruz Thomas D, Valdes Ana M, Santiago Alma, Frazer de Llado Teresa, Raffel Leslie J, Zeidler Adina, Rotter Jerome I, Erlich Henry A, Rewers Marian, Bugawan Teodorica, Noble Janelle A
Abstract excerpt
Genetic associations between type 1 diabetes and alleles at the HLA class II locus DPB1 have been previously reported. Observed associations could be due to variation in the DPB1 locus itself or to linkage disequilibrium (LD) between DPB1 alleles and other susceptibility loci. One measure of whether the association of an allele with a disease reflects a true effect of the locus or is simply due to LD is the...
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