Article
Ctf4p facilitates Mcm10p to promote DNA replication in budding yeast.
Biochemical and biophysical research communications - 7 May 2010
Wang Jiafeng, Wu Rentian, Lu Yongjun, Liang Chun
Abstract excerpt
Ctf4p (chromosome transmission fidelity) has been reported to function in DNA metabolism and sister chromatid cohesion in Saccharomyces cerevisiae. In this study, a ctf4(S143F) mutant was isolated from a yeast genetic screen to identify replication-initiation proteins. The ctf4(S143F) mutant exhibits plasmid maintenance defects which can be suppressed by the addition of multiple origins to the plasmid, like other...
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