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Article

Ctf4 coordinates the progression of helicase and DNA polymerase alpha.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jul 2009

Tanaka Hirokazu, Katou Yuki, Yagura Masaru, Saitoh Katsuya, Itoh Takehiko, Araki Hiroyuki, Bando Masashige, Shirahige Katsuhiko

Abstract excerpt

Ctf4 is a protein conserved in eukaryotes and a constituent of the replisome progression complex. It also plays a role in the establishment of sister chromatid cohesion. In our current study, we demonstrate that the replication checkpoint is activated in the absence of Ctf4, and that the interaction between the MCM helicase-go ichi ni san (GINS) complex and DNA polymerase alpha (Pol alpha)-primase is destabilized...

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Source

Identifiers

PMID: 19496828
DOI: 10.1111/j.1365-2443.2009.01310.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ctf4 coordinates the progression of helicase and DNA polymerase alpha.PMID 19496828Read ↗

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