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Article

The Mcm2-7-interacting domain of human mini-chromosome maintenance 10 (Mcm10) protein is important for stable chromatin association and origin firing.

The Journal of biological chemistry - 4 Aug 2017

Izumi Masako, Mizuno Takeshi, Yanagi Ken-Ichiro, Sugimura Kazuto, Okumura Katsuzumi, Imamoto Naoko, Abe Tomoko, Hanaoka Fumio

Abstract excerpt

The protein mini-chromosome maintenance 10 (Mcm10) was originally identified as an essential yeast protein in the maintenance of mini-chromosome plasmids. Subsequently, Mcm10 has been shown to be required for both initiation and elongation during chromosomal DNA replication. However, it is not fully understood how the multiple functions of Mcm10 are coordinated or how Mcm10 interacts with other factors at...

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Identifiers

PMID: 28646110
DOI: 10.1074/jbc.M117.779371
PMCID: PMC5546039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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