Article
Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability.
Genes to cells : devoted to molecular & cellular mechanisms - 1 May 2003
Araki Yoshio, Kawasaki Yasuo, Sasanuma Hiroyuki, Tye Bik K, Sugino Akio
Abstract excerpt
BACKGROUND: MCM10 is essential for the initiation of chromosomal DNA replication in Saccharomyces cerevisiae. Mcm10p functionally interacts with components of the pre-replicative complex (Mcm2-Mcm7 complex and origin recognition complex) as well as the pre-initiation complex component (Cdc45p) suggesting that it may be a component of the pre-RC as well as the pre-IC. Two-dimensional gel electrophoresis analysis...
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