Article
The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication.
The Journal of biological chemistry - 8 Mar 2013
Santosa Venny, Martha Sabrina, Hirose Noriaki, Tanaka Katsunori
Abstract excerpt
The minichromosome maintenance (MCM) complex is a replicative helicase, which is essential for chromosome DNA replication. In recent years, the identification of a novel MCM-binding protein (MCM-BP) in most eukaryotes has led to numerous studies investigating its function and its relationship to the MCM complex. However, the mechanisms by which MCM-BP functions and associates with MCM complexes are not well...
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- Adaptor Proteins, Signal Transducing
- Amino Acid Sequence
- Blotting, Western
- Cell Cycle
- Cell Cycle Proteins
- Chromosomes, Fungal