Effects of the nucleotide 3' to an amber codon on ribosomal selection rates of suppressor tRNA and release factor-1.

doi:10.1016/0022-2836(91)90564-m

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Article

Effects of the nucleotide 3' to an amber codon on ribosomal selection rates of suppressor tRNA and release factor-1.

Journal of molecular biology - 20 May 1991

Pedersen W T, Curran J F

Abstract excerpt

Rates of ribosomal selection of both release factor 1 (RF1) and a suppressor tRNA (Su7C33) were studied at an amber codon at which the 3' neighbor was permuted. Rates of RF1 selection vary 2.6-fold among contexts. The 3' neighbor-dependent variation of RF1 action correlates very strongly with the non-random frequencies of 3' neighbors at UAG terminators (r = 0.97), which argues that the rate of RF1 selection is...

Topics

Base Sequence
Codon
Escherichia coli
Escherichia coli Proteins
Genes, Suppressor
Genetic Variation
Models, Genetic
Molecular Sequence Data
Oligonucleotide Probes
Peptide Termination Factors
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Promoter Regions, Genetic

RNA, Transfer

RNA, Transfer, Amino Acyl

Ribosomes

Terminator Regions, Genetic

Source

Open in PubMed

Identifiers

PMID: 2038055
DOI: 10.1016/0022-2836(91)90564-m

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2038055-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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